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Perncious anemia is caused by the body's inability to absorb the vitamin B12 from the gastrointestinal tract, due to a loss of gastric parietal cells. Regular B12 supplementation can keep pernicious anemia at bay, though it is not a complete cure. B12 is a vitamin obtained from meat and dairy products.
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∙ 12y ago
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Explain the relation between vitamin b12 and pernicious anemia?
first of all its called vitamin b12 deficiency anemia. Pernicious anemia and vitamin B12 deficiency anemia are the same thing. Pernicious anemia is caused by a lack of vitamin B12. You're not able to absorb the vitamin B12 due to the absence of intrinsinc factor.
Inadequate intrinsic factor is associated with?
due to lack of b12 No HCl and intrinsic factor = pernicious anemia
What is the disease caused by the lack of minerals?
There are many. The most common is rickets in the young, osteoporosis in the old, and is caused by a lack of calcium. Anemia is the result of iron deficiency. A separate form of anemia (pernicious anemia) is due to cobalt deficiency.
Lack of vitamin b?
Beriberi is caused by a lack of vitamin B1, pellagra by a lack of vitamin B3, while pernicious anemia is due to a lack of vitamin B12. A lack of Vitamin B is simply called a Vitamin B Deficiency.
Why oral administration of vitamin B12 not effective as a treatment of pernicious anemia?
Pernicious anemia is due to a deficiency of a vitamin called intrinsic factor, which is normally produced by cells of the stomach. Intrinsic factor is required for the absorption of vitamin B12, so if intrinsic factor levels are insufficient, vitamin B12 will not be absorbed well. So administration of vitamin B12 will only help treat vitamin B12-deficiency anemia if vitamin B12 can be absorbed, and this can only happen if there are adequate levels of intrinsic factor to begin with. Patients with pernicious anemia do not have adequate intrinsic factor levels, so they will not be helped by vitamin B12 treatment since they can't absorb it well enough.
What is pernicious anemia and it's symptoms?
This is anaemia (lowered blood haemoglobin) due to a lack of vitamin B12 absorbed from the intestinal tract, due to a lack of intrinsic factor usually. This can be due to auto antibodies against the cells that produce intrinsic factor, stomach ulcers crowding out the cells that produce intrinsic factor, a hereditary lack of intrinsic factor or the after effects of surgery, illness or fish tapeworm. This gives a macrocytic anaemia. Pernicious anemia is an autoimmune disease that renders the person unable to absorb sufficient Vitamin B-12. Eventually the person becomes Vitamin B-12 deficient and must be treated. Prior to the availability of treatment persons died from the disease, hence the name pernicious. It is critical that treatment be obtained as soon as possible. You can find more information at the following website: www.pernicious-anaemia-society.org
How many types of anemia are here?
There are several types of anemia. The term means without blood. It could be caused by excessive bleeding or damage to the bone marrow. Anemia is one of the most common disorders of the blood. It can be due to excessive blood loss or hemorrhage. Or deficient red blood cell production. Anemia can be classified in several ways: macrocytic anemia, normocytic anemia, microcytic anemia. Some of the more familiar ones are: pernicious anemia due to lack or low B12, iron deficiency anemia due to lack of iron, thalassemia, lead toxicity anemia, hypothyroidism, aplastic anemia, sickle cell anemia, Rh disease, and renal infection among others.
Who gets Pernicious anemia?
Pernicious or megaloblastic anemia is mainly caused due to deficiency of either Vitamin B12, or Folic acid or both. risk groups are pregnant lady(mainly folate is the cause) strict vegetarian(vit b12 is only found in animal sources) malabsorbtion syndrome(like problem with enteric factor of castle).
What is perniciousness?
This is anaemia (lowered blood haemoglobin) due to a lack of vitamin B12 absorbed from the intestinal tract, due to a lack of intrinsic factor usually. This can be due to auto antibodies against the cells that produce intrinsic factor, stomach ulcers crowding out the cells that produce intrinsic factor, a hereditary lack of intrinsic factor or the after effects of surgery, illness or fish tapeworm. This gives a macrocytic anaemia. Pernicious anemia is an autoimmune disease that renders the person unable to absorb sufficient Vitamin B-12. Eventually the person becomes Vitamin B-12 deficient and must be treated. Prior to the availability of treatment persons died from the disease, hence the name pernicious. It is critical that treatment be obtained as soon as possible. You can find more information at the following website: www.pernicious-anaemia-society.org
What is pernicious anemea?
This is anaemia (lowered blood haemoglobin) due to a lack of vitamin B12 absorbed from the intestinal tract, due to a lack of intrinsic factor usually. This can be due to auto antibodies against the cells that produce intrinsic factor, stomach ulcers crowding out the cells that produce intrinsic factor, a hereditary lack of intrinsic factor or the after effects of surgery, illness or fish tapeworm. This gives a macrocytic anaemia. Pernicious anemia is an autoimmune disease that renders the person unable to absorb sufficient Vitamin B-12. Eventually the person becomes Vitamin B-12 deficient and must be treated. Prior to the availability of treatment persons died from the disease, hence the name pernicious. It is critical that treatment be obtained as soon as possible. You can find more information at the following website: www.pernicious-anaemia-society.org
Disease caused due to lack of vitamin A?
night blindness is cuased due to the lack of vitamin eye .
What is the reason of having a anemia?
Two major forms of Anemia have been found in biological sciences, the "Megalo-Blastic Anemia" caused due to deficiency of Vitamin B 12 or the Cyano- Cobalamine and thye other one being the "Pernicious Anemia" caused due to lack of Iron in the diet. Women are more prone to the anemic conditions as they loose blood cells frequently and are mostly diet conscious which may lead to deprivation of iron minerals in there body. In certain cases, the first type caused due to B 12 deficiency may be linked to chromosomes and hence may show phenomena of inheritance.
