The major target of aldosterone is the distal tubule of the kidney, where it stimulates exchange of sodium and potassium. Three primary physiologic effects of aldosterone result:
Knowing these effects should quickly suggest the cellular mechanism of action this hormone. Aldosterone stimulates transcription of the gene encoding the sodium-potassium ATPase, leading to increased numbers of "sodium pumps" in the basolateral membranes of tubular epithelial cells. Aldosterone also stimulates expression of a sodium channel which facilitates uptake of sodium from the tubular lumen.
Increased sodium reabsorption, and since water follows sodium it also increases water reabsorption in kidneys.
Aldosterone: A hormone made by the outer portion (cortex) of the adrenal gland that regulates the balance of salt and water in the body.
It increase the reabsorption of Na+.So blood pressure is increased.
Aldosterone measurement is useful in detecting a condition called aldosteronism, which is caused by excess secretion of the hormone from the adrenal glands. There are two types of aldosteronism: primary and secondary.
Aldosterone will cause Na+ to be absorbed from a filtrate
Aldosterone promotes water retention and reduces urine volume
Aldosterone helps to indirectly regulate blood levels. A low sodium diet is a way to increase aldosterone in the body.
It decreases the affect of aldosterone secretion.
Aldosterone is a hormone, so it gets to the kidneys via the blood stream.
Aldosterone causes sodium to be retained and potassium to be excreted and blood pressure to rise.
Aldosterone is sensitive to a few different things. The main thing it is sensitive to is the kidneys.
ADT
Aldosterone
Aldosterone measurement is useful in detecting a condition called aldosteronism, which is caused by excess secretion of the hormone from the adrenal glands. There are two types of aldosteronism: primary and secondary.
Aldosterone is regulated by negative feedback system except in cases of dehydration in which high sodium levels stimulate more production of aldosterone. Normally negative feedback regulates production.