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The first sign of antifreeze poisoning in dogs you'd probably see is what looks like drunken behavior

Other signs you might see are:

Wobbly, uncoordinated movement, nausea or vomiting, excessive urination and possibly diarrhea, rapid heart beat, weakness, and possibly seizures or convulsions.

For immediate first aid, and only if you are positive that your dog has drank antifreeze, try to induce vomiting by giving your dog a simple hydrogen peroxide solution (one teaspoon per five pounds of body weight, with no more than three teaspoons given at once). This method should only be used if the toxin has been ingested in the previous 2 hours, and should only be given 3 times, spaced apart at 10-minute intervals. If your pet has not vomited after the third dose, stop giving it the hydrogen peroxide solution and seek immediate veterinary attention.

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Q: What are the symptoms of anti freeze poisoning in dogs?
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