Currently about 30 different blood group systems are known in humans but the ones of clinical significance are the ABO system, Rh system, Kell, MNS, Lewis etc.
The importance of blood group systems lies in transfusion and transplant medicine as we can receive blood (or organ) from only an individual whose blood group matches ours. In case of mismatch, the body's immune system recognizes the 'foreign' antigen and fights it leading to disease states.
People without Kell antigens (K0), must be transfused with blood from donors who are also K0 to prevent hemolysis (breaking down RBCs).
The K (K1) antigen (antibody) is very immunogenic and causes strong reactions in case of mismatched blood transfusion and severe fetal anemia in sensitized mothers.
It is produced only after exposure to the antigen as a result of pregnancy or repeated blood transfusions.
Antibody K is an antibody that connects to the Kell antigen on a red blood cell.
With "unknown antibodies" you might mean irregular antibodies. In this case probably anitibodies against K (anti-K) a subtype of the Kell-bloodtype. Causes could be (including but not limited to): - You got a transfusion of bloodcells - You were pregnant
S. K. Ross has written: 'Antibodies as artificial bio-catalysts'
Antibodies
Vaccines stimulate production of antibodies.
primarily B antibodies and Rh antibodies
No they do not. B cells synthesize the antibodies.
Antibodies are made in the lymph nodes.
Antibodies respond to pathogens.
Function of antibodies is to neutralizes the antigens that enters.
antibodies fight infections
An example of a protein that helps fight off infection is antibodies.
Antibodies will eventually form but it takes 7-10 days for that to happen.