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The central dogma of molecular biology was first enunciated by Francis Crick in 1958[1] and re-stated in a Nature paper published in 1970:[2] : The central dogma of molecular biology deals with the detailed residue-by-residue transfer of sequential information. It states that information cannot be transferred back from protein to either protein or nucleic acid. In other words, 'once information gets into protein, it can't flow back to nucleic acid.' The dogma is a framework for understanding the transfer of sequence information between sequential information-carrying biopolymers, in the most common or general case, in living organisms. There are 3 major classes of such biopolymers: DNA and RNA (both nucleic acids), and protein. There are 3×3 = 9 conceivable direct transfers of information that can occur between these. The dogma classes these into 3 groups of 3: 3 general transfers (believed to occur normally in most cells), 3 special transfers (known to occur, but only under specific conditions in case of some viruses or in a laboratory), and 3 unknown transfers (believed to never occur). The general transfers describe the normal flow of biological information: DNA can be copied to DNA (DNA replication), DNA information can be copied into mRNA, (transcription), and proteins can be synthesized using the information in mRNA as a template

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15y ago
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11y ago

The central dogma of DNA, also known as the central dogma of molecular Biology describes the sequence DNA -> RNA -> Protein. This is important because it shows the process of creating proteins from DNA and is the process by which cells regulate their functions.

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7y ago

In molecular biology, as in biology in general, the "central dogma" establishes the normal pathway observed in all living forms in the planet from genes to proteins. This central dogma is the "cornerstone" to understand the biology mechanisms of life. This central dogma settle in: DNA (or deoxyribonucleic acid) is a double strand molecule that keeps the inherit information in a succession of nucleotides that form genes, specific sequences of DNA that will be translated into a particular characteristic in the organism. The genes are "copied" into a single strand molecule called mRNA (or messenger ribonucleic acid) in a process called "transcription" occurring in the nucleus. The genetic information in the mRNA will give a protein (in theory, one protein per each gene) in a process called "translation" that takes place in the ribosome in the cytoplasm of the cell. A simple diagram illustrates this dogma: DNA D RNA " PROTEIN This means that eventually RNA molecule can go back to form a DNA molecule in a process called “reverse transcription”. There is no possibility to go back from protein to form neither an RNA molecule, nor a DNA one. This central dogma works for al living organisms, microbes, plants and animal forms, in planet Earth.

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Q: What is the importance of central dogma?
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Is there any online quiz for central dogma of molecular biology?

Yes, there are a few quizzes for central dogma under the related links.


Is both DNA and RNA involved in the central dogma of biology?

Yes. The central dogma of biology postulates: DNA < > RNA > Proteins


What does the central dogma help us to explain?

A central dogma is an explanation of the flow of the genetic information in a cell, including the replication of DNA.


What is central dogma in a short brief simply?

Flow of information for the synthesis of protein through a series of processes like transcription and translation is called central dogma.


What is a sentence using the word dogma?

Central dogma of biology is life. This is one of many examples for sentence use.


What is also known as protein synthesis?

central dogma


Why central dogma called central dogma?

That was a somewhat satirical name Francis Crick gave to the process that he helped develop an elucidation of. There are no true dogmas in biology, though RNA -> DNA -> protein is very much the general process, reverse transcription rather " destroys " the central dogma.


Is central dogma of molecular biology can be reversed or not?

it should be reversed


What is the the theory that describes protein building in this order?

Central Dogma


What is an exception to the central dogma of molecular biology?

The "central dogma" states information goes from DNA to RNA to Protein in a retrovirus it goes from RNA to DNA back to RNA to Protein. The central dogma as it is called has so many exceptions now that it is no longer considered central.


Are both DNA and rna are involved in the central dogma of biology?

Yes


The part of the central dogma occurs in the cytoplasm of eukaryotic cells?

translation