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If it's a placebo it is by definition very unlikely to work if the patient is aware it's a placebo. Prescribing a placebo to an unaware patient would be unethical (at least under UK guidelines)

Additionally the benefits of a placebo in a condition where the pathology of the disease has few emotional components are likely to be limited. Placebos tend only to work on conditions with an "emotive" component; that is some form of downwards regulatory pathway from higher centres which can be activated to supress symptoms. For example perception of pain has a large higher control component (via the peri-aqueductal grey matter) which can be activated by placebo analgesics.

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Q: What types of placebo medications are there for someone with alzheimers?
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