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Because the Native Americans weren't immune to the disease that the Spanish gave then. The disease was small pox by the way.

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12y ago
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6mo ago

Disease, particularly smallpox, killed a significant number of Native Americans when the Spanish arrived because the Indigenous populations had no immunity to these new diseases. They had not been previously exposed to them, while Europeans had built up some level of resistance over centuries. This lack of immunity allowed diseases brought by the Spanish to spread rapidly and ravage Native American communities.

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Q: Why did disease kill off so many native Americans when the Spanish first arrived?
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Related questions

What proved to be the largest killer of Native Americans after the Spanish arrived?

disease


What disease caused the most native American deaths after the spanish arrived?

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Smallpox is the disease that caused the death of Native Americans. The Spanish conquistadors brought it from Spain, and the Native Americans, not having an immunity to it, died when the Spanish invaded the Aztec capital. This helped the Spanish defeat the Aztec capital and take over what is known today as Mexico.Bubonic Plague


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