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Why does a mother dog kill her own puppies at 5 weeks old?

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This is very abnormal behavior for a female dog. Potential causes include behavioral problems in the mother, frank starvation of the mother or major deformities in the puppies. Regardless of the cause, this female should not be bred again - spaying to prevent future pregnancies would be a good idea.
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What if mother dog kills puppy?

wrong you have to separate them for a couple weeks or moths then see how it turns out put them back together if the mom try to kill one then you really need to call the vetena

Why would a mother show aggression toward her 5 week old puppies?

At five weeks old the puppies are getting old enough to be weened. She may just be telling them enough with the breast feeding already! Often a good mother will shut her pups