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stratified squamous has many layers of cells; more mature cells at the top and younger cells near the base. it is seen in lumen's and organs that have high abrasion rates. the esophagus moves food bolus from the mouth to the stomach, the 'abrasion' caused by the food passing down through the stomach causes rubbing of the lining which removes cells. thus the esophagus needs many layers of cells so that it can withstand this abrasion and make more cells to replace those lost.

note though, that the esopagus at the bottom 3rd (usually past the diaphragm layer) is made of tall columnar cells to deal with the refluxing stomach acid. Barretts esophagus is a premalignant condition where this epithelia spreads further up the esophagus and causes much pain to the person!!

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13y ago
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9y ago

The structure and function of the organ go hand in hand. The stratified squamous epithelium helps to tolerate the ware and tear of transmission of food bolus.

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Q: Why is the esophagus lined with stratified squamous epithelium as opposed to simple columnar epithelium?
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