Take I-64 EAST to I-57 SOUTH. .
Continue on I-57 SOUTH to I-24 EAST to NASHVILLE at EXIT 44. .
Take I-24 EAST through Illinois and Kentucky and through Nashville to I-75 SOU…TH to ATLANTA at EXIT 185A in Chattanooga. .
Take I-75 SOUTH through Tennessee and Georgia to I-10 to JACKSONVILLE and TALLAHASSEE at EXIT 435 in FLORIDA. On this stretch, bypass Atlanta, Georgia by taking I-285 WEST BYPASS (EXIT 259 off I-75 and then EXIT 58 off I-285 to get back onto I-75 SOUTH) and bypass Macon, Georgia by taking I-475 SOUTH (EXIT 177 off I-75). .
Follow signs to I-10 EAST to JACKSONVILLE. Take I-10 EAST to Jacksonville. (MORE)