Your simplest scheme would be to wire them in series - one after
the other - thus presenting a 16 ohm load to the amplifier. This
will cause no harm to the amplifier.
If you wired them in parallel, then the effective load would be
only 4 ohms, and this would cause more load on the amplifier.
Depending upon the design of your amplifier, this could cause more
distortion.
In closing, it is only in the 'mid range' that the impedance of
the speaker is the nominal load - say 8 ohm. At 'resonance' -
generally at frequencies of a few tens of Hertz, the impedance of
your speaker will be a few times its nominal impedance. At high
frequencies, again the impedance of the speaker will increase to a
few times nominal.