You can be affected by Penile cancer even if you don't or haven't had Penile cancer.
For example- say their was a lady called Sue and she had a daughter called Olivia but Sue also has Penile cancer. Olivia would also be affected. It would affect her in a sad kind of way. I mean Olivia would be worried and upset.
So Penile cancer can also affect those without Penile cancer just as much as it dose affect those who do have Penile cancer. So you really should not make jokes about anything to do with Penile cancer, unless everyone is OK with you making the joke and won't get upset and tell on you.