1 unit prp increases platelet count by 10,000.

fresh frozen plasma by Fc receptor blockade will inhibit immune mediated destruction of platelets and thereby increase the platelet count

potassium

It's not the PRP that needs approval from the FDA, it is the machine or centrifuge that processes the blood that needs approval. The machine has to go through the FDA to get a 510k clearance for the preparation of platelet rich plasma for human use. From their each company has different procedures that they are cleared for (and some they are not).

Platelet rich in fibrin (PRF) is known to have several advatages over platelet rich plasma PRP) including:

1-Unlike PRP, with PRF no anticoagulant or/and antiplatelet therapy is needed, hence diminishing risks for bleeding.

2-PRP is effective when used on soft tissue only, while PRF could be utelized in treatments plans for both soft and hard tissue.

3-PRF is prepared faster and easier, rendering PRP less time effective.