Eureka Seven , Serial Experiments Lain , Mahou Shoujo Madoka Magieca , Bokurano ,

Yes it is. Other than bizarre or confusing sci-fi moments, there are a few scary or disturbing moments in the anime.

Ergo Proxy , Texhnolyze , Serial Experiments Lain , Wolf's Rain , the Ghost in the Shell films and series , and the anime films Pale Cocoon and Angel's Egg .

Motoko Kusanagi from the Ghost in the Shell films and series is one of the best female protagonists in all of anime , Re-L from Ergo Proxy , Robin Sena of Witch Hunter Robin and Lain Iwakura from Serial Experiments Lain are all strong female leads .

Among some of the more serious anime series you will find Ghost in the Shell (films and series) , Ergo Proxy , Tehxnolyze , Serial Experiments Lain , Cowboy BeBop , Wolf's Rain and others .