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Definition

Strongyloidiasis is infection with the roundworm Strongyloides stercoralis (S. stercoralis).

Causes, incidence, and risk factors

S. stercoralis is a roundworm that is fairly common in warm, moist areas. Rarely, it can be found as far north as Canada.

People catch the infection when they come in contact with soil contaminated with the worms.

The tiny worm is barely visible to the naked eye. Young roundworms can move through a person's skin and into the bloodstream to the lungs and airways. As the worms grow older, they bury themselves in the walls of the intestines. Later, they produce eggs in the intestines. Areas where the worms go through the skin may become red and painful.

This infection is uncommon in the United States. Most cases seen in North America are brought by travelers who have visited or lived in South America or Africa.

Symptoms

Most of the time, there are no symptoms.

If there are symptoms, they may include:

Signs and tests

The following tests may be done:

  • Blood antigen test for S. stercoralis
  • Complete blood count with differential
  • Duodenal aspiration to check for S. stercoralis
  • Sputum cultureto check for S. stercoralis
  • Stool sample exam to check for S. stercoralis
Treatment

The goal of treatment is to eliminate the worms with anti-worm medications such as ivermectin.

In some cases, such as in those who will be taking immunosuppressive drugs, people with no symptoms are treated.

Expectations (prognosis)

Full recovery with eradication of parasites is expected with adequate treatment. Sometimes treatment needs to be repeated.

Infections that are widespread often have a poor outcome, especially in people with weakened immune systems.

Complications
  • Acute pulmonary eosinophilia (Loeffler's syndrome)
  • Disseminated strongyloidiasis, especially in patients with HIV or an otherwise compromised immune system
  • Malnutrition due to problems absorbing nutrients from the gastrointestinal tract (malabsorption)
Calling your health care provider

Call for an appointment with your health care provider if you have symptoms of strongyloidiasis.

Prevention

Good personal hygiene can reduce the risk of strongyloidiasis. Adequate public health services and sanitary facilities provide good control of infection.

ReferencesKazura JW. Nematode infections. In: Goldman L, Ausiello D, eds.Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 378.
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Definition

Strongyloidiasis is infection with the roundworm Strongyloides stercoralis (S. stercoralis).

Causes, incidence, and risk factors

S. stercoralis is a roundworm that is fairly common in warm, moist areas. Rarely, it can be found as far north as Canada.

People catch the infection when they come in contact with soil contaminated with the worms.

The tiny worm is barely visible to the naked eye. Young roundworms can move through a person's skin and into the bloodstream to the lungs and airways. As the worms grow older, they bury themselves in the walls of the intestines. Later, they produce eggs in the intestines. Areas where the worms go through the skin may become red and painful.

This infection is uncommon in the United States. Most cases seen in North America are brought by travelers who have visited or lived in South America or Africa.

Symptoms

Most of the time, there are no symptoms.

If there are symptoms, they may include:

Signs and tests

The following tests may be done:

  • Blood antigen test for S. stercoralis
  • Complete blood count with differential
  • Duodenal aspiration to check for S. stercoralis
  • Sputum cultureto check for S. stercoralis
  • Stool sample exam to check for S. stercoralis
Treatment

The goal of treatment is to eliminate the worms with anti-worm medications such as ivermectin.

In some cases, such as in those who will be taking immunosuppressive drugs, people with no symptoms are treated.

Expectations (prognosis)

Full recovery with eradication of parasites is expected with adequate treatment. Sometimes treatment needs to be repeated.

Infections that are widespread often have a poor outcome, especially in people with weakened immune systems.

Complications
  • Acute pulmonary eosinophilia (Loeffler's syndrome)
  • Disseminated strongyloidiasis, especially in patients with HIV or an otherwise compromised immune system
  • Malnutrition due to problems absorbing nutrients from the gastrointestinal tract (malabsorption)
Calling your health care provider

Call for an appointment with your health care provider if you have symptoms of strongyloidiasis.

Prevention

Good personal hygiene can reduce the risk of strongyloidiasis. Adequate public health services and sanitary facilities provide good control of infection.

ReferencesKazura JW. Nematode infections. In: Goldman L, Ausiello D, eds.Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 378.
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The 3 human infecting roundworms are called Strongyloidiasis, Brugia timori and Ascaris lumbricoides :)

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Threadworm infection, which is also called strongyloidiasis, occurs in most countries of the world but is natural to (endemic in) tropical and subtropical climates.

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Edoardo Perroncito has written:

'Rhabdonema strongyloides Leuckart-Anguillula intestinalis e Pseudorhabditis stercoralis' -- subject(s): Human beings, Strongyloidiasis, Rhabditida, Intestines, Parasites

'La Tubercolosi dei bovini in rapporto alla tubercolosi umana' -- subject(s): Tuberculosis

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Ankylostomiasis caused by hookworms, two nematodes in humans, Anccylostoma duodenalis and Necator americanus. The infected human release in the feces the eggs to the ground, the egg grows to lavae and matures, this larvae is the infectious stage to humans and have the hability to penetrate human skin and access bloodstream. In bloodstream they migrate through lungs and then to the small intestine where they evolve to adults, reproduce and release eggs. The adult also suck blood from the small intestine wall causing the disease.

Strongyloidiasis caused by a nematode called Strongyloides stercoralis. They have a similar biological cycle to the hookworms but they release larvae in feces and the adult lives in tunnels in the mucosa of the small intestine. There´s also posibility of autoinfection from larvae released in the small intestine. The disease may be asymptomatic at first but in immunocompromised individuals strongyloidiasis can cause a hyperinfective syndrome which is severe, inmunosupressive drugs are associated with this.

Trichuriasis caused by Trichuris trichiura or human whipworm: The human gets infected through accidental ingestion of eggs found in the earth and can contamine water and food. The egg evolves, first in the small as larvae and then in the large intestine to adult where they reproduce and release the eggs through feces.

Trichinosis, caused by a nematode Trichinella spiralis. Human gets infected by eating pig flesh containing larvae in muslce tissue. In the intestine, larvae evolve to adult which live in the mucosa and release larvae.

Fascioliasis caused by Fasciola hepatica, a trematode. The human gets infected by ingesting vegetables that grow in water where the larvae stick on these vegetables. The larvae ultimately reach the liver and grows to adult causing symptoms.

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