There are many places where one can find information on creating a web based business. There are many tutorials on business creation sites such as Volusion.

brick and morter

(Web-based) A web application is an application that is accessed over a network such as the Internet or an intranet. The term may also mean a computer software application that is hosted in a browser-controlled environment

Web based applications runs on browsers and we can access it remotely from anywhere in world. You may find some terrific web based business applications on http://awebdesk.com .

Biz is the web domain for a business (.biz).

UK is United Kingdom.

So, it looks like you are referring to a business web address based in the UK.