Cutoff age is generally around 5 or 6 years old, before they become a "senior" and the earliest you should ever breed a female should be their third season. For both guidelines this is because breeding and whelping are harder on their bodies before or after that time. And of course the health and safety of your female should be your first concern.
I don't suggest breeding to a boxer... stick to their own breed. If you are trying to produce puppies with traits, body structure, or markings that the boxer has and your female doesn't... try to find that in another American Bulldog. Physically yes it would work and I don't have anything against boxers, they are a wonderful breed, but there is no reason to cross breed when each breed has their own qualities that don't need to be changed. Every breed in the world has their own health risks, however I am not a vet and you should always research the breed, talk to established quality breeders and always talk to your vet and even get a few other vets opinions.
hope this helps, good luck and just remember it's a lot of work breeding, make sure you're doing it for the right reasons.
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Experts estimate between 200 & 600 American Crocidiles still exist in the wild.
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