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A recessive gene located on the X chromosome is the cause of muscular dystrophy in affected individuals. Males are more likely to suffer from muscular dystrophy than females because?
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Using a punnett Square explain why males are affected more often than females by sex linked genetic disorders?
This is a very short compared to the X chromosome with which it is pair. In X-linked genetic disorders (such as Duchenne's muscular dystrophy}. In the x an y type of sex determinate organisms, the genes affecting the expression are only located on X-chromosome, the y chromosome does not have its contrasting allelic gene. Hence, when a female organism has a recessive gene(for example colorblindness), its another X chromosome obtained from male gamete will mask the expression, and the female will escape color blindness. In case of male, the x-chromosome carrying a gene for colorblindness from its mother will have its expression because its counterpart (y-chromosome) does not carry its allelic form. Hence although the genes cause defects are carried by females, the males are affected more. This can be explained by drawing a Punnett Square for male and female gametic fusion possibilities.
Why are female carriers?
Females carry two X chromosomes; males only carry one. A female carrier carries a defective recessive allele for a gene on the X chromosome. Thus, the female will not be affected because she still has a copy of the dominant allele. However, if she has any male children, that child will be affected because males inherit their X chromosome from their mothers.
Why do Males tend to be affected in greater numbers by X-linked recessive genetic disorders than females?
males have only one X chromosomes
Which specific population is affected by Turner syndrome?
The population affected is females. The chromosome that this affects is on the X chromosome which is the sex chromosome that females carry. This affects 1 in every 2,500 live births.
Why Are males more often hemophiliac?
Hemophilia is a recessive, sex-linked, X chromosome disorder. It would have to be present on both X chromosomes to present in females. It only has to be present on the single X chromosome to present in males.
A recessive gene located on the X chromosome is the cause of hemophilia in affected individuals. Males are more likely to have hemophilia than females because?
Males only have one copy of the X chromosome
What gene is affected by type 1 diabetes?
Chromosome 2
What chromosome is affected by meckel syndrome?
Meckel Syndrome (type 1)is an autosomal recessive trait carried on chromosome 17.
Is muscular dystrophy inherited?
Duchenne muscular dystrophy inheirited recessively meaning it is not passed nessicerially every generation. DMD is recessive it explain why boys commonly get it, affeted fathers pass it on to 50% of daughters and none of his sons assuming the mother is normal. The daughters aren't affected by the disease but they passes it on to 50% own sons and none of there daughters assuming the father is normal.
Who is affected by muscular dystrophy?
Someone whose parent is a carrier of the gene; because the gene is on the X chromosome which is inherited by your mother it would most likely be from her.
What is the prognosis for individuals that have the classic form of myotonic dystrophy?
Affected individuals that have the classic form have a more severe prognosis. They have more clinical manifestations and lifespan usually ranges 48-55 years.
What causes color blindness genetically?
The majority of affected individuals are males. Females are carriers, but are not normally affected. This indicates that the X chromosome is one of the locations for color blindness.
In albinism what chromosome number is affected?
Chromosome 9.
What chromosome number is affected by hypercholesterolemia?
chromosome 19
What chromosomes can be affected by changes in chromosome numbers?
Any chromosome can be affected by aneuploidy. However, generally, the larger the chromosome, the larger the likelihood that the change in chromosome number will be fatal.
What body systems are affected by muscular dystrophy?
The body systems that are affected by muscular dystrophy include the nervous system and the musculoskeletal system. Many organs are also affected by this genetic disorder.
How is sickle cell anemia inherited?
This is inherited on the X chromoseome and is recessive. This means a female (who has XX chromosome pair) can only express the disease if she carries the trait on both chromosomes. This is because of the recessive nature of the gene. A male can only inherit the disease from his mother. This is he must have obtained his Y chromosome from his father so he obtains the X chromosome from his mother. A male cannot carry the gene without expressing it as he doesnt have another X chromosome to supress the recessive gene. ^ This answer is biologically incorrect because Sickle cell Anemia is actually autosomal recessive, not sex-linked recessive; this means that males and females are affected equally and it is NOT carried on the X chromosome. In order for the trait to show up in an individual, BOTH parents must be carriers of the disease (at least 1 sickle cell gene must be present).
