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males have only one X chromosome, so if they inherit the gene for muscular dystrophy on that X chromosome, they will develop the disorder. Females have two X chromosomes, so they would need to inherit the gene on both chromosomes to be affected, making it less likely for them to show symptoms.
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Under what condition can a female acquire an X recessive disorder?
Both X chromosomes must carry the recessive trait. Since males only have one X chromosome, it is much easier for males to have the recessive phenotype. Put another way, a female would have to receive an X chromosome with the recessive gene from both parents, which would mean the father already displays the recessive disorder.
Discuss the inheritance pattern that would be seen in a pedigree designed to study a recessive sex-linked trait?
In a pedigree designed to study a recessive sex-linked trait, affected individuals are more commonly male because they inherit the trait on their X chromosome from their carrier mother. Females need to inherit two copies of the gene (one from each parent) to be affected. The trait skips generations and can be passed down from carrier females to affected males.
Using a punnett Square explain why males are affected more often than females by sex linked genetic disorders?
This is a very short compared to the X chromosome with which it is pair. In X-linked genetic disorders (such as Duchenne's muscular dystrophy}. In the x an y type of sex determinate organisms, the genes affecting the expression are only located on X-chromosome, the y chromosome does not have its contrasting allelic gene. Hence, when a female organism has a recessive gene(for example colorblindness), its another X chromosome obtained from male gamete will mask the expression, and the female will escape color blindness. In case of male, the x-chromosome carrying a gene for colorblindness from its mother will have its expression because its counterpart (y-chromosome) does not carry its allelic form. Hence although the genes cause defects are carried by females, the males are affected more. This can be explained by drawing a Punnett Square for male and female gametic fusion possibilities.
Is hunters disease dominant or recessive?
Hunter's disease is inherited in an X-linked recessive pattern. This means the mutated gene that causes the disease is located on the X chromosome, and males are more commonly affected because they only have one X chromosome. Females can carry the mutated gene but are typically unaffected due to having a second X chromosome that can compensate.
Why do Males tend to be affected in greater numbers by X-linked recessive genetic disorders than females?
males have only one X chromosomes
What type of allele is responsible for causing duchenne muscular dystrophy?
Duchenne muscular dystrophy is caused by a recessive allele on the X chromosome. This means that males are more commonly affected since they only have one X chromosome. Females can carry the allele but are usually not affected due to having a second X chromosome that often carries a normal copy of the gene.
A recessive gene located on the X chromosome is the cause of hemophilia in affected individuals. Males are more likely to have hemophilia than females because?
Males only have one copy of the X chromosome
What gene is affected by type 1 diabetes?
Chromosome 2
What chromosome is affected by meckel syndrome?
Meckel Syndrome (type 1)is an autosomal recessive trait carried on chromosome 17.
Why are omen often carriers of x linked traits but rarely affected by them?
Omen, or male individuals, often carry X-linked traits because they possess only one X chromosome, inherited from their mother. If that X chromosome carries a recessive trait, they will express it, but if they carry a dominant trait, they may not be affected if it is also present on the Y chromosome or if the trait is recessive. In contrast, female individuals have two X chromosomes, making them more likely to express or be affected by X-linked traits, especially if they inherit two copies of a recessive trait. Thus, while omen can carry X-linked traits, they are less frequently affected due to the nature of X-linked inheritance.
Why is pseudohypertrophic muscular dystrophy not to be expected in girls?
Pseudohypertrophic muscular dystrophy, commonly known as Duchenne muscular dystrophy (DMD), is primarily caused by mutations in the dystrophin gene located on the X chromosome. Since boys have only one X chromosome, they are more likely to express the disease when the gene is mutated. In contrast, girls have two X chromosomes, which means they would need mutations in both copies to exhibit the condition; this is much less common. As a result, girls are often carriers of the disorder rather than affected individuals.
Under what condition can a female acquire an X recessive disorder?
Both X chromosomes must carry the recessive trait. Since males only have one X chromosome, it is much easier for males to have the recessive phenotype. Put another way, a female would have to receive an X chromosome with the recessive gene from both parents, which would mean the father already displays the recessive disorder.
Why will a male inhert x liked recessive gene from is dad?
A male inherits his X chromosome from his mother and his Y chromosome from his father. Therefore, he cannot inherit an X-linked recessive gene directly from his dad, as fathers pass their Y chromosome to their sons. If a male has an X-linked recessive condition, it must come from his mother, who can pass on the affected X chromosome. In summary, males inherit X-linked traits only from their mothers.
Who is affected by muscular dystrophy?
Muscular dystrophy primarily affects the muscles and can impact individuals of all ages. It is a genetic condition that causes progressive weakening and loss of muscle mass, leading to mobility issues and potentially affecting various bodily functions. The severity of the condition can vary greatly among those affected.
What are traits controlled by non sex genes on the sex chromosome?
Traits controlled by non-sex genes on the sex chromosomes (primarily the X chromosome) include various genetic disorders and traits such as color blindness, hemophilia, and certain types of muscular dystrophy. These traits can be inherited regardless of the sex of the individual, as they are linked to genes located on the X chromosome. Since males have only one X chromosome, they are more likely to express these traits when they inherit a recessive allele, while females may be carriers if they have one normal and one affected allele.
Discuss the inheritance pattern that would be seen in a pedigree designed to study a recessive sex-linked trait?
In a pedigree designed to study a recessive sex-linked trait, affected individuals are more commonly male because they inherit the trait on their X chromosome from their carrier mother. Females need to inherit two copies of the gene (one from each parent) to be affected. The trait skips generations and can be passed down from carrier females to affected males.
Using a punnett Square explain why males are affected more often than females by sex linked genetic disorders?
This is a very short compared to the X chromosome with which it is pair. In X-linked genetic disorders (such as Duchenne's muscular dystrophy}. In the x an y type of sex determinate organisms, the genes affecting the expression are only located on X-chromosome, the y chromosome does not have its contrasting allelic gene. Hence, when a female organism has a recessive gene(for example colorblindness), its another X chromosome obtained from male gamete will mask the expression, and the female will escape color blindness. In case of male, the x-chromosome carrying a gene for colorblindness from its mother will have its expression because its counterpart (y-chromosome) does not carry its allelic form. Hence although the genes cause defects are carried by females, the males are affected more. This can be explained by drawing a Punnett Square for male and female gametic fusion possibilities.
