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Why do Males tend to be affected in greater numbers by X-linked recessive genetic disorders than females?
males have only one X chromosomes
What else can I help you with?
This pedigree is for a human genetic disease called sickle cell anemia. Assuming that the allele for the disease is recessive how many of the females shown have the disease?
None. =]
How do you recognize a pedigree for an x-linked recessive allele in human beings?
For a recessive sex-linked trait to manifest in women it would have to be in double dose (XaXa) while for men in single dose (XaY). Women carriers would have one of each but would not be affected (XAXa). Knowing this it's quite easy to spot pedigrees where this kind of inheritance occures.Heterozygote mothers (gene carrier) can have sons that are affected (50% chance);Affected mothers have only affected sons (100%);No first generation daughter of an heterozygote mother will be affected but there is a 50% chance that she is a carrier;Affected fathers with normal mothers will have zero sons that are affected but all their daughters will be carriers;
Using a punnett Square explain why males are affected more often than females by sex linked genetic disorders?
This is a very short compared to the X chromosome with which it is pair. In X-linked genetic disorders (such as Duchenne's muscular dystrophy}. In the x an y type of sex determinate organisms, the genes affecting the expression are only located on X-chromosome, the y chromosome does not have its contrasting allelic gene. Hence, when a female organism has a recessive gene(for example colorblindness), its another X chromosome obtained from male gamete will mask the expression, and the female will escape color blindness. In case of male, the x-chromosome carrying a gene for colorblindness from its mother will have its expression because its counterpart (y-chromosome) does not carry its allelic form. Hence although the genes cause defects are carried by females, the males are affected more. This can be explained by drawing a Punnett Square for male and female gametic fusion possibilities.
Under what condition can a female acquire an X recessive disorder?
Both X chromosomes must carry the recessive trait. Since males only have one X chromosome, it is much easier for males to have the recessive phenotype. Put another way, a female would have to receive an X chromosome with the recessive gene from both parents, which would mean the father already displays the recessive disorder.
Discuss the inheritance pattern that would be seen in a pedigree designed to study a recessive sex-linked trait?
In a pedigree designed to study a recessive sex-linked trait, affected individuals are more commonly male because they inherit the trait on their X chromosome from their carrier mother. Females need to inherit two copies of the gene (one from each parent) to be affected. The trait skips generations and can be passed down from carrier females to affected males.
What form of Niemann Pick can be inherited?
All forms of NPD are inherited autosomal recessive disorders, requiring the presence of an inherited genetic mutation in only one copy of the gene responsible for the disease. Both males and females are affected equally.
A pedigree chart for color blindness?
In a pedigree chart, color blindness is typically represented by shading in the symbol of affected individuals. Males are usually shown as squares and females as circles. The inheritance pattern of color blindness is usually X-linked recessive, where males are more commonly affected than females. The chart can help track how the condition is passed down through generations in a family.
Why are males often affected more than females by sex-linked genetic disorders?
males have only one X chromosomes
What evidence is there that the long and round did not become blended?
A number of genetic disorders are caused when an individual inherits two recessive alleles for a single-gene trait. Recessive genetic disorders include Albinism, Cystic Fibrosis, Galactosemia, Phenylketonuria (PKU), and Tay-Sachs Disease. Other disorders are also due to recessive alleles, but because the gene locus is located on the X chromosome, so that males have only one copy (that is, they are hemizygous), they are more frequent in males than in females.
Why are sex linked recessive conditions more likely in males then females?
Sex-linked recessive conditions are more likely to occur in males because they only need to inherit one copy of the affected gene in order to exhibit the condition (as they have one X chromosome). Females, on the other hand, have two X chromosomes, so they need to inherit two copies of the affected gene to exhibit the condition.
Traits determined by recessive genes located on the x chromosomes are said to be?
Some traits are determined by recessive genes on the X chromosomes. Many times these are genetic disorders and are called recessive genes.
What evidence is there that the long and round alleles did not become blended?
A number of genetic disorders are caused when an individual inherits two recessive alleles for a single-gene trait. Recessive genetic disorders include Albinism, Cystic Fibrosis, Galactosemia, Phenylketonuria (PKU), and Tay-Sachs Disease. Other disorders are also due to recessive alleles, but because the gene locus is located on the X chromosome, so that males have only one copy (that is, they are hemizygous), they are more frequent in males than in females.
What evidence is there that the long round allels did not become blended?
A number of genetic disorders are caused when an individual inherits two recessive alleles for a single-gene trait. Recessive genetic disorders include Albinism, Cystic Fibrosis, Galactosemia, Phenylketonuria (PKU), and Tay-Sachs Disease. Other disorders are also due to recessive alleles, but because the gene locus is located on the X chromosome, so that males have only one copy (that is, they are hemizygous), they are more frequent in males than in females.
Which race has more problems with eating disorders?
Caucasian females between the ages of 15 and 26. However, all races and age groups are affected.
How do you know if a trait is sex linked dominant or sex linked recessive?
A trait is sex-linked dominant if it appears in every generation and affects both males and females. It is sex-linked recessive if it skips generations, more common in males, and passed from carrier females to affected males. Mendelian inheritance patterns can help determine if a trait is sex-linked dominant or sex-linked recessive.
This pedigree is for a human genetic disease called sickle cell anemia. Assuming that the allele for the disease is recessive how many of the females shown have the disease?
None. =]
Is pku sex linked recessive or sex dominant?
I think I read somewhere that there are some variants of it that are recessive and others that are dominant.
