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It can. It is possible to get a small bladder infection at first if you are female. This is called "honeymoon cystitis". Honeymoon cystitis is one term for a urinary tract infection. The majority of sufferers are female, and it's not uncommon for a woman to develop cystitis on her honeymoon. Left untreated, it can lead to a bladder and kidney infection.
Symptoms of honeymoon cystitis may include a burning or painful sensation during urination, the urge to urinate frequently, cloudy urine, blood-tinged urine, and/or pain above the pubic bone - any of which will put a damper on honeymoon lovemaking.
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