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any gene that is a causative factor in the initiation of cancerous growth
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∙ 14y ago
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How does a proto-oncogene differ from an oncogene?
Compare with a virus: dormant to active, potential to kinetic, potent(ial) to actual. The proto-oncogene may become a cancer-causing oncogene only under very specific conditions and may, under other conditions, just as well lay dormant.
What effect does oncogenes have on cells?
Cells with an oncogene become over-stimulated to divide more often than normal. The chances of cancer developing are increased if a mutation to a tumor-suppressor gene also occurs. As an oncogene is a cancer-causing gene
What are three genetic changes that can convert proto-oncogenes to oncogenes?
Movement of DNA within the genome, amplification of a proto-oncogene, and point mutations in a control element or in the proto-oncognene itself.
What enzyme is referred to as Akt?
Akt is the enzyme which is known as protein kinase B. Its scientific term is thymoma viral proto-oncogene and its particular job is to help promote cellular revival.
What is the function of the KRAS gene?
The K-ras (perhaps sometimes called the KRAS) gene is an oncogene which activates mutations that will play a key role in diseases such as lung, colorectal, and pancreatic cancer.
When was Oncogene - journal - created?
Oncogene - journal - was created in 1987.
How does a protooncogene converted into an oncogene?
A proto-oncogene is normally converted to an oncogene by mutation of the gene that encodes the proto-oncogene. Often, this leads to de-regulation of the proto-oncogenes activity and typically abarrent signal transduction in the cell, which may lead to cellular transformation.
What is pro- oncogene?
An oncogene is a gene, when mutated or expressed at high levels it helps turn a normal cell into a tumor cell.
What is the term for a cancer gene?
Oncogene.
How does a proto-oncogene differ from an oncogene?
Compare with a virus: dormant to active, potential to kinetic, potent(ial) to actual. The proto-oncogene may become a cancer-causing oncogene only under very specific conditions and may, under other conditions, just as well lay dormant.
A mutant of a regulatory gene that causes cancer?
oncogene
A gene having the potential to trigger cancerous changes in a cell?
oncogene
What gene cause cancer when present in a single copy in a cell?
oncogene
What process is the protein product of the Ras proto oncogene involved in?
you will have to be more specific There is a point mutation in the k-ras oncogene, and about 60% have a mutation in the p53 so you can develop cancer in the colon by many polyps.
What is a mutation that forms an oncogene that changes normal cells into cancerous cells?
to a gene
What is the p35 cancer gene?
tumor suppresser gene that could turn into an oncogene
What kinds of somatic cell gene mutations can frequently lead to the first stages of cancer?
Proto-oncogene is the kind of somatic cell gene mutation that can lead to first stages of cancer. Proto-oncogene can lead to cellular transformation.
