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They were initially thought to be stable and harmless as they had low reactivity (hence stable), were non toxic and non flammable and so found wide spread use as refrigerant gasses (heat exchangers). However it was later discovered that in the upper atmosphere they were broken down by photons (light) to liberate Chlorine and helped to cause the break down of ozone to O2 which is a much less effective barrier to UV leading to the creation of "holes" in the ozone layer.

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