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Depressant drugs include opium, opium derivatives, drugs synthesized from opiates, synthetic opiates (that do not require an opiate precursor), tranquilizers, barbiturates, alcohol and a variety of lesser-known drugs. All are potentially addictive, and the ones listed are highly addictive.

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14y ago
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15y ago

Addiction to tranquilizers requires fairly continuous use for a long enough period to alter the structure of certain cells in the brain -- usually a period of weeks. However, we suppose it is possible that one could like the effects enough to become psychologically addicted in a short time. It is unlikely, however, that it would happen after one use (if you mean one dose).

You should know that withdrawal from some tranquilizers is extremely dangerous. If you or someone you know is addicted, we encourage a supervised medical detox to avoid the possibility of seizures and psychotic episodes.

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14y ago

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In studies looking at the abuse liability of drugs in animals and humans "tranquilizers" tend to be moderately addictive. In comparison cocaine and amphetamines consistently rank as highly addictive (more so than all other substances). In animal models mice addicted to cocaine will, when given unlimited access, use until they die. None of the various classes of tranquilizers (primarily barbiturates and benzodiazepines) pose that level of addiction. On the other hand tranquilizers cause the most significant physical dependency (alone this is NOT addiction) and tolerance of all drugs. Up to 1/2 of people using tranquilizers long term becomes physically dependent but psychological dependency (addiction) is uncommon and 80% of people with a tranquilizer abuse problem have a comorbid substance abuse problem (heroin, methadone, cocaine, amphetamines).

It should also be noted that antipsychotics (neuroleptics), commonly called "major tranquilizers," are NOT substances of abuse.

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You can't really qualify how addictive something is. Addiction is different for everyone. If you are into uppers, tranquilizers will probably not appeal to you. If you are into downers, addiction to tranquilizers could sneak right up on you.

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14y ago

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Q: Are all tranquilizers addictive
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