The Spanish Influenza of 1918-1920.
The 30.cal machine gun.
According to wikipedia it was World War 2 with 70 million people killed, most of whom were civilians. http://en.wikipedia.org/wiki/World_War_II
Well, technically speaking, Nazi Germany did by far since they killed so many Jewish people.
Although it is now eradicated I believe it was smallpox.
Ciudad Juarez, Mexico is dangerous. About 85 people a day are killed.
Most of those killed were gassed to death.
Most were killed from the explosion, some survived but may have short term or long term radiation illness which can be terminal.
According to recent research, the animal that kills the largest amount of people is the Theraphosa Blondi. The Theraphosa Blondi is a ten-inch long spider, that attacks whatever it sees that moves. I wouldn't want to run into one of those in a dark alley!
The disease that killed most of Edgar Allan Poe's female family members was tuberculosis. It was a common and deadly illness during that time period, and sadly, it took the lives of many people, including Poe's loved ones.
Most people are killed in earthquakes due to collapsing buildings or structures, falling debris, or tsunamis triggered by undersea earthquakes. Additionally, hazards such as landslides, fires, and gas leaks can also contribute to the number of fatalities.
No telling, some countries had multimillion's of deaths. Most by gunfire.
World War II had an incredibly larger number of deaths if including both civilian and military loss of life. In the second World War, over 60 million people were killed, and in the first World War, approximately 37 million people were killed.