The best route is avoiding LA as much as possible. You will find that highway 5 is better than 99 to go south, since the freeway is wider, more shoulder, higher speed limits and better maintained roads. However on highway 5 the grapevine area can offer weather concerns in winter. I like to take advantage of highway 5 south until highway 138, and cut over to 99 before the grapevine. If driving through LA after 9pm, take highway 5 all the way to the 210, to the 10 to palm springs. If driving through LA any time between 5am and 9pm you WILL hit traffic, the kind that takes 45minutes to get 5 miles, so skip LA and go through lancaster down into yucca valley.
You need to take I-80 E towards Sacremento. It'll take about a day to drive it.
Route-66 is the best driving route from Los Angeles to Ontario Canada
The quickest and shortest route is I-5 North.
www.mapquest.com will provide the best route.
What is the most direct driving route from Nice France to Marseilles
I-95 to I-10 to I-25
Just go up Route 611.
When traveling it is important to know which route is best. To get from Vancouver to Calgary, the best route would be to take the Trans Canada Highway 1.
a road
I would take Ca-99 down to Ca-120 and ultimately towards Yosemite National Park. It'll be a 160 mile drive and take about 3 hours and 30 minutes.
Right after the morning rush hour. 9 AM.
The best driving route from Calais to the Czech Republic is one that avoids going through Brussels. It takes about 11 hours to drive the distance.