Best way to drive from Destin Fl to St. Louis Mo?

Answer 1

1. Take I-55 SOUTH through Missouri, Arkansas, Tennessee (Memphis) and Mississippi (through Jackson) to I-12 EAST to SLIDELL at EXIT 29A in Louisiana.
2. Take I-12 EAST to I-10 EAST to BAY St. Louis at EXIT 85C.
3. Take I-10 EAST through Louisiana, Mississippi and Alabama to FL-87 to FT. WALTON BEACH and NAVARRE at EXIT 31 in Florida.
4. Turn right off the exit ramp onto FL-87 SOUTH to FT. WALTON BEACH and NAVARRE. Take FL-87 SOUTH to US-98. Turn left onto US-98 EAST.
5. Take US-98 EAST to Destin. Destin is just after Ft. Walton Beach.

Answer 2

1. Take I-10 EAST to FL-85 to CRESTVIEW and NICEVILLE in Florida.
2. Turn right off the exit ramp onto FL-85 SOUTH to NICEVILLE. Take FL-85 SOUTH to US-98 in Ft. Walton Beach.
3. Turn left onto US-98 EAST. Take US-98 EAST to DESTIN.