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Q: Can Low IGG3 and low IGG4 cause peripheral neuropathy?
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What does elevated immunoglobulin g mean?

Elevated IgG4 levels will sometimes point to allergic diseases, asthma and cystic fibrosis. Without knowing more about other lab results, it is impossible to discern a specific problem just from an elevated IgG level. Some people also just tend to have normal levels on the outlying edges of laboratory normal.


What does an elevated immunoglobulin indicate?

High IgG levels does not lead to a diagnosis without further details of the types of IgG which are elevated. An increase in certain IgG subclasses is associated with diseased states especialy IgG4 in allergic diseases, asthma and cystic fibrosis. With the wording used in the question it could imply that the person is mearly at the outlying area of normal distribution (reference range), just as some people are "tall" some people have naturally high IgG titers. On the plus side a high IgG titer means it is highly unlikely (but not impossible) that the patient has any immunodeficient diseases associated with IgG.


Are you born with hemophilia?

Hemophilia is passed down from mother to son. It is extremely rare for a woman to have hemophilia. It is necessary, though, for a woman to be a carrier of the disorder for her son to acquire this disorder. Females have two X chromosomes whereas males only have one. When a boy is born, he takes one X chromosome from his mother and one Y chromosome from his father. Therefore, he can only get hemophilia through his mother. Example One: Mother(Carrier)+Father(Non-Affected)=50% chance of their son acquiring the disorder and 50% chance of their daughter being a carrier. Example Two: Mother(Non-Affected)+Father(Hemophiliac)=All sons will be non-affected and all daughters will be carriers.


Chronic cholecystitis?

cholecystitis is inflammation of the gallbladder that develops over hours, usually because a gallstone obstructs the cystic duct. Symptoms include right upper quadrant pain and tenderness, sometimes accompanied by fever, chills, nausea, and vomiting. Abdominal ultrasonography detects the gallstone and sometimes the associated inflammation. Treatment usually involves antibiotics and cholecystectomy.