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Metronidazole is a special kind of antibiotic that is aimed at so called anaerobic bacteria. These bacteria do not need oxygen for growth. When you are suffering from sinusitis, most likely other bacteria are involved. So therapy with metronidazole as a single agent can definitely not be recommended. The antibiotics of choice are amoxycillin (or ampicillin) i.g. combined with clavulanic acid. Other antibiotics that should work well are doxycyclin or the macrolides like erythromycin or azithromycin

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12y ago
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13y ago

I have never heard of this being used for a sinus infections. This medicine does NOT work for FLU, VIRUSES or COLDS.. usually associated with a sinus infection.

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13y ago

Yes, because Metronidazole is an anti bacterial agent, which hava many uses, including respiratory tract infections.

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Q: Can Metronidazole 500mg be used for a sinus infection?
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What do you use if amoxicillin does not cure your sinus infection?

Amoxicillin and metronidazole are to be taken in combination for a sinus infection. If plain amoxicillin does not work, a formulation with clavulanic acid such as augmentin should be used with metronidazole.


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Apen is a penicillin-based antibiotic used to treat infection.


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