In general, yes. But it might be necessary to change jets, power valves, metering rods, or vacuum springs depending on the type of carb being used.
There are books available through Amazon and others that describe in detail how to fine tune your brand of carb.
U little pig
"The v8 350 is a small block Chevrolet motor.....................it became a big block at 396cubic inches......so anything smaller is a "small" block" this is a little misleading. a 350 is indeed a small block. a 396 is indeed a big block. but you can have a small block that is (internally..cubic inch wise) actually larger than a big block. for example GM made a 400 cubic inch small block. internally it is a larger engine than a 396, but the outer dimensions of the 396 are larger than the 400 small block. and the external dimensions and cylinder head design are what make a small block a small block, and a big block a big block. a small block engine simply has a physically smaller block...a big block is called a big block because it's block is bigger than that of a small block.
Small block
It is a small block
One is big. One is Small.
A 350 is a small block and all the engine parts are small. The 454 is a big block and everything is big. Nothing will interchange.
Big block
Pontiac uses same block no small or big, Chevy describes their engines small or big
That would be a small block.
It is a small block.
BIG BLOCK OR SMALL BLOCK DOES NOT DEPEND ON CUBIC INCHES . IT IS THE DESIGN OF THE BLOCK ITS SELF.
Windsor 351, is a small block. 351 Cleveland, is a big block. The 351M, stands for "modified" and is a windsor (small) block, with Cleveland (big block) heads.