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For the most part, no. Dogs with Allergies tend to have skin and gastrointestinal tract issues, not the upper respiratory signs shown by humans. Therefore, giving a dog Benadryl to reduce allergy-related inflammation is probably not going to do anything to resolve an eye issue. However, a veterinarian who has examined your dog and determined the cause of the eye issue may prescribe Benadryl for your dog.

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Q: Can a dog take Benedryl if they have glaucoma?
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