Yes, it is possible. It depends of course of the individual's sensitivity to that particular antigen.
IgM.
The letters of the blood types are assigned by the number of antigens in the person's blood. A and B are used because they are the first two letters of the alphabet. O is used to signify zero, as in zero antigens.
The normal RDW ( width of each Red Blood Cell) level is 10.2 to 14.5%. It is important to keep in mind that the ranges mentioned above will be different depending on the machine used to do the blood test. Immunoglobulin M, or IgM for short, is a basic antibody that is produced by B cells. It is the first antibody to appear in response to initial exposure to an antigen (foreign substance).
The first contact of a T or B cell with its specific antigen is called priming. It causes differentiation into effector T or B cells.
Innate is a broad general response against any pathogen. It is very quick response but it is limited in how well it can defend your body. It is absolutely necessary to have a functioning innate immunity or your adaptive immunity will not be able to respond efficiently. Adaptive has a very specific response against a pathogen. On first exposure it may time several weeks to acquire the appropriate defenses, however, on secondary exposure it is a very quick response. It has long term memory so you are protected for a long time against that same pathogen.
Memory B cells and memory T cells carry the record of the first exposure to an antigen in the body. These cells are generated during the initial immune response and remain in the body to provide a faster and stronger immune response upon re-exposure to the same antigen.
During the first exposure to an antigen antibodies are produced
The class of immunoglobulin to respond to the fist exposure of an antigen is immunoglobulin class M (IgM). While Immunoglobulin G (IgG) would predominate on the second exposure.
IgM is produced upon initial exposure to an antigen. For example, when a person receives the first tetanus vaccination, antitetanus antibodies of the IgM class are produced 10 to 14 days later. IgM is abundant in the blood.
After your first exposure to a pathogen, you have memory T-cells that will remember the antigen of the pathogen so in the future if you would come in contact with the same pathogen your body would recognize it right away and be able to kill it much faster.
antigen
Yes. The first signal that a T cell receives from an antigen presenting cell (dendritic cell) is MHC presenting an antigen (foreign peptide). This gives the T cell specificity to this antigen.
Primary versus Secondary Immune ResponseThe primary immune response occurs the first time that the immune system comes in contact with the antigen. During this time the immune system has to learn to recognize antigen and how to make antibody against it and eventually gain immunological memory. This primary response takes time (about two weeks) and during this time the person experiences signs of illness. IgM antibodies are the hallmark of a new infection because they are the first antibodies made when a person is exposed to an antigen for the first time. After the body learns to make IgM antibodies, it will start making IgG antibodies to the antigen.The secondary immune response occurs the second time (3rd, 4th, etc.) the person is exposed to the same antigen. At this point immunological memory has been established and the immune system can start making antibodies immediately. The antigen usually is killed within minutes and the person is not aware that he/she was attacked. The antibodies in this response are IgG and IgA or (in the case of allergy IgE).
Lgm
Generally accepted to be 1838 or 1839, by Louis Daguerre. The unknown person stopped to have his shoes shined during the 10 minute exposure. If not for this, his presence, like everyone else in the street, would not have been captured due to the long exposure.
Because antibodies that cause the reaction are not naturally occurring. One has to be exposed to Rh in order to make antibodies to it. Its the same process as the reaction to a vaccine. The vaccine exposes you to an antigen and your body learns how to react to it in order to protect you from it. If you are exposed to the Rh factor, your body learns how to react to it, and so the next time you're exposed, the reaction is greater. The major blood groups are different. The antibodies occur naturally. A group O person typically has antibodies to blood from group A and group B donors. Whereas a group AB person doesn't have these antibodies. Also, there are lesser known antigen/antibody groups that can cause trouble. That's what makes my job in the Blood Bank more interesting.
IgM.