No, they are entirely two different things. What might stimulate a receptor could be an antigen.
an aepitope is the part of an antigen where antibodiy or lymphocyte receptor binds
Helper T cells recognize the receptor-antigen complex and cause plasma and memory cells to be produced to then produce antibodies.
In short, CD3 is a transmembrane protein found on T lymphocytes that functions in signal transduction following antigen stimulation of the T cell receptor.
a receptor
Another term for univalent antigen
the antigen must bind to the receptor
The glycoprotein CD4 is a co-receptor. A co-receptor is "a cell surface receptor, which, when bound to its respective ligand, modulates antigen receptor binding or affects cellular activation after antigen-receptor interactions." (MediLexicon)
The Burnet theory about antigen antibody reaction is a basic concept about how we make antibodies specific to a foreign substance which has the ability to induce an immune response (antigen). Each B cell displas one unique type of B cell receptor on their surface (which is basically a membrane bound antibody). Therefore many B cells, each expressing its own type of B cell receptor are needed to cover the inexhaustable number of antigens that are possible, in the hope that one type of B cell receptor will be able to recognise the shape of that antigen. If one B cell does recognise the antigen in question, then this B cell will become activated to make many clones of itself, which will obviously carry identical B cell recptors which fit the antigen. |Therefore the clonal selection theory by Burnet is about antibody antigen interactions which result in the 'best-fit' B cell receptor inducing a reaction to tell the B cell carrying the receptor to multiply and produce lots of identical antibodies which can then be secreted to bind to the antigen they are specific for.
an aepitope is the part of an antigen where antibodiy or lymphocyte receptor binds
there are different types of b cell and t cell. both are lymphocytes, a subclass of white blood cell. the t cells are mainly used in identifying antigens and releasing chemicals which attact macrophages (big immune cells which 'eat' antigens), to destroy the antigen. b cells are used in the production of antibodies. when they encounter a new antigen, plasma cells and memory cells are formed from the division of a b cell. the memory cell remembers the antigen and which antibody to use, while the plasma cell makes the antibodies to fight a particular antigen or class of antigens
Helper T cells recognize the receptor-antigen complex and cause plasma and memory cells to be produced to then produce antibodies.
Pamela Sumiko Ohashi has written: 'Molecular analysis and expression of T cell antigen receptor genes'
In short, CD3 is a transmembrane protein found on T lymphocytes that functions in signal transduction following antigen stimulation of the T cell receptor.
Judith Ann Henwood has written: 'T-cell receptor expression in antigen-specific human T-cell clones'
A antigen
CD4 is a surface receptor expressed by helper T lymphocytes, known as CD4+ T cells. Its purpose is to stablize the interaction between the T cell receptor (on the T cell) and an antigen-bearing MHC Class II molecule (on an antigen presenting cell). Under the right circumstances, this interaction activates CD4+ T cells that recognize an invading pathogen. Activated CD4+ T cells do many things, and are required for a robust adaptive immune response.
The first signal required to activate a T cell is MHC(Major Histocompatibility Complex) presenting an antigen(foreign peptide) to the T cell receptor.