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Because studies are still investigating the effects of Depression there is not yet firm evidence to support or deny that this could happen. What those experts say is that the Depression does exist through chemical changes where some of those required to lift mood, reduce the survival reaction etc are not working effectively. There is a possibility that when the body, which is after all made up of chemicals finds that these chemicals are out of balance then there is sufficient reason to believe that other chemicals can be effected indirectly.

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Q: Can depression lead to a weak immune system in adults?
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