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No. Diphenhydramine HCL is the generic name for "Benadryl", a decongestant.

Actually yes it can. If you take high concentrations of it. it can produce a false positive, if you do research on the internet you will fins some say yes and some say no , but i know first hand from experince, the answer is 100% yes.

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13y ago
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14y ago

Absolutely not. Drugs are screened for by the metabolites or 'leftover' pieces of the drug.
THC and Benadryl are two very different things, and will not have the same resulting substance.

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Wiki User

11y ago

Diphenhydramine HCl is the active ingredient in Benadryl, an over the counter antihistamine drug used for Allergies and hives. It will not provide it's users with a "high" but will cause substantial drowsiness. In fact, it is the active ingredient in Unisom and many other over the counter sleep aids.

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12y ago

Not normally. It is an ingredient in several over-the-counter medications including Benadryl and some sleep aids.

While I say not normally, it depends on how sensitive of a test they are running. If tested further at a higher quality lab they can show that it is one of these OTC medications.

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14y ago

No. It would depend on what they're testing for, but if you are trying to pass a "drug test" as usually referred to, dyphenhydramine wouldn't show up.

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Q: Can Diphenhydramine cause a positive urine test?
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