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It can, but 20mg is just not enough methadone to be any danger especially if she has been taking it for a prolonged period. Methadone is usually safe to take with most other drugs, but everyone is different and has different drug Allergies. It is important to talk to your physician or pharmacist to find any drug interactions.

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Q: Can methadone cause sickness or fatality with any other drug interaction including over counter prescribed or street drugs. My mom is prescribed 10 mg twice a day. She is 70 and I Would like 2 know?
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