0
Implanted polypropylene mesh (PP) in a large subset of patients causes a chronic foreign body reaction (FBR). The tissues around the implant are damaged by the oxidation process used by the body to try rid the body of the biomaterial that is not being accepted by the patients' body.
The degradation products of the oxidation are free hydroxyl radicals. The oxidation process degrades the PP and it can become brittle, shrink and have brittle edges fragment and migrate in the patient. Patients experience mesh migration, erosions, extrusions, chronic infections and many symptoms of Implant Syndrome. A simple explanation would be to compare this process as to how a splinter festers and gets moved out of the body. Chemical irritation added to mechanical irritation sets the body up for a state of constant inflammation. The immune system is constantly trying to attack the foreign body, as well as infections safely encapsulated with the mesh implant that cells trying to attack the bacteria cannot penetrate because of encapsulation or small mesh fiber size the cells cannot enter. States of chronic inflammation are associated with autoimmune disease pathogenisis, and cancer. A lack of long term studies regarding the systemic response of PP mesh degradation has left patients to research and share their health status with each other. Many report they have been diagnosed with Lupus, Rheumatoid Arthritis, and Fibromyalgia post mesh implantation. Many report developing Asthma post mesh implantation, and those with pre-existing autoimmune diseases before PP mesh implantation find their autoimmune disease symptoms exacerbated post mesh PP implantation.
Wiki User
∙ 10y ago
Anonymous
Yes it can. Immune responses can be recurring infections. Formation of biofilms as the body tries to protect it self. Septecemia often follows from recurring infections of the biofilm. Degradation of the materials that enter the blood stream. Polypropylene in the brain. Yes it does cross the blood brain barrier. Arthritis, Gravis, and other immune responses have been reported.
Anonymous
Yes
Add your answer:
Earn +20 pts
Why do you have tonsils?
it is part of your immune system but the seem like they cause many problems
What is the definition for innate immune deficiency?
when a person is born with an immune system that doesn't function, the body is unable to fight and survive infections by pathogens that don't cause any problems for a robust immune system.
Food safety affects with immune system problems?
Food safety affects the entire body because food poisoning and food-borne illness can caused major problems. These attack the immune system and can cause it to weaken.
What is brain tissue damage?
These are called lesions. Brain lesions can be caused by injury, infection, exposure to certain chemicals, problems with the immune system, and more. Typically, their cause is unknown.These are called lesions. Brain lesions can be caused by injury, infection, exposure to certain chemicals, problems with the immune system, and more. Typically, their cause is unknown.
Can ovarian cysts cause high blood pressure?
Ovarian cysts can cause high blood pressure in the sense that they can cause weaken a person's immune system and cause problems in the long run over time.
What are effects of high levels of Uv light?
Too much exposure can cause skin burns and skin cancer
How does Systemic Lupus Erythematosus cause seizures?
In systemic lupus, the immune system can attack any part or system of the body. If the person's immune system attacks their own central nervous system the results can include seizures, personality changes, depression, neuropathy, cognitive problems (difficulty thinking or remembering), and psychosis.
What happens to red blood cells that are agglutinated?
red blood celld that are agglutinated are destroyed by the immune system. If they remain in your system as damaged it is unhealthy. This is because it can cause major problems such as organ failure.
Can chickenpox cause the immune system to progressively fail?
No, progressive failure of the immune system is not an effect of chickenpox. HIV infection is one communicable disease that causes progressive failure of the immune system.
What is a system that fights disease and controls the immune response?
It is called the Immune System. A bit of extra info: The Immune System is the cause of allergies. It goes too far when trying to protect the body from something. ENDOCRINE SYSTEM
What can cause your immune system to fight itself?
passive immunity
What is the system that fight diseases and controls the immune response?
It is called the Immune System. A bit of extra info: The Immune System is the cause of Allergies. It goes too far when trying to protect the body from something. ENDOCRINE SYSTEM
