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No. The antidepressant class of medications does not possess addictive properties. There is no tolerance or dependence that occurs (as can be the case with benzodiazepines, opiates, amphetamines, barbiturates and others).

That being said, there are two antidepressant medication which possess a discontinuation syndrome. Flu-like symptoms, myalgia, fatigue and other symptoms, may occur for a few days (or even a week or so, in some cases, but not true withdrawal effects. The two medications which can produce this are paroxetine (Paxil) and venlafaxine (Effexor), and, to a lesser extent, desvenlafaxine (Pristiq).

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Q: Can someone become addicted to antidepressant medications?
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