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Yes. For example, the chemical structure of water molecules is such that the oxygen atom has a slight negative charge, while the hydrogen atoms have a slightly positive charge. This is because oxygen atoms are much larger and more electronegative than hydrogen atoms. So the oxygen atom holds the shared electrons more closely than do the hydrogen atoms. This type of chemical bond is called polar covalent because the electrons are shared unequally, causing a slightly negative pole at one end and a slightly positive pole at the other end. As a result, water molecules are attracted to one another, and this attraction is called a hydrogen bond. Because of this, water has very unique properties compared to other molecules of similar size.

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Q: Can the chemical structure of a compound affect properties such as strength of attraction to other molecules?
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