Despite all their best efforts, they could not save his life.
The football match went ahead despite the rain.
He passed the exam, despite forgetting to revise for it.
It is used when a person does something even when he has been forewarned about something or, when a person repeats a mistake though he was punished for the same, before.
For example, "In spite of telling him not to come, John came today."
Or, "Mindy went out to play in spite of getting scolded the previous time".
"In Spite Of" also means the same as "despite".
Tony continued to draw on his bedroom wall despite being told not to by his mum and dad.
Despite the possible outcomes, Cass ate Chef Hugo's chocolate.
I lasted until the very finish, despite my detractor's loud protestations.
Despite the immense heat, the girls played a game of soccer.
Despite the teacher's wishes, the boys wrote on the board.
Despite common knowledge, the boy said.
He went ahead despite his broken leg. This proves his commitment to work.
Here are some sentences.
Despite the rain, we enjoyed the game.
She passed the exam despite her mistake.
I called, despite your wishes.
union is a strategy.
He is very humble despite his achievements.
"despite Peter's initial hesitance, he finally moved on"
Despite insurmountable obstacles in his life, he had done very well.
Despite his German citizenship, he always considered himself more of a Frenchman.
I shall carry on, despite your ill will.
He remained loyal to the government despite their treatment of him. His loyal service was rewarded with a medal.
The alarm clock buzzed persistantly, despite my attempts to turn it off.
She got the job despite her bad behavior during the interview.
Despite thinking about it I couldn't think of a sentence for establishment
I can give you a sentence using the word galaxy.