<ol><li>Take SR-395 (Waddy Rd) NORTH to I-64 EAST.</li><li>Take I-64 EAST to I-77 SOUTH. I-64 joins with I-77 in Charleston, West Virginia, then they split near Beckley. From there you want to continue SOUTH on I-77.</li><li>Take I-77 SOUTH to I-74 EAST to MOUNT AIRY and WINSTON-SALEM at EXIT 101 in North Carolina.</li><li>Take I-74 EAST to U.S. 52 SOUTH. Continue STRAIGHT on U.S. 52 SOUTH.</li><li>Take U.S. 52 SOUTH to I-40 EAST to GREENSBORO and HIGH POINT at EXIT 107A just past downtown Winston-Salem.</li><li>Take I-40 EAST to I-73 SOUTH to ASHEVILLE outside of WINSTON-SALEM.</li><li>Continue SOUTH on I-73 to where it temporarily ENDS at U.S. 220. From there take U.S. 220 SOUTH to U.S. 1 SOUTH, go straight and then take U.S. 1 SOUTH to I-74/U.S. 74 EAST.</li><li>Take I-74/U.S. 74 EAST to ROUTE 38 to HAMLET and BENNETTSVILLE at EXIT 319.</li><li>Turn right off the exit ramp onto ROUTE 38 SOUTH towards BENNETTSVILLE.</li><li>Take ROUTE 38 into South Carolina and then stay on ROUTE 38 SOUTH to U.S. 501 SOUTH. It will be a seamless connection.</li><li>Take U.S. 501 SOUTH to SR-22 (Conway Bypass) EAST to MYRTLE BEACH and NORTH MYRTLE BEACH. SR-22 is about 8 miles past the town of Aynor.</li><li>Take SR-22 around Conway on the Conway Bypass to the EXIT for SR-31 (Carolina Bays Pkwy) SOUTH to MYRTLE BEACH.</li><li>Take SR-31 SOUTH back to U.S. 501 SOUTH. EXIT LEFT.</li><li>Continue on U.S. 501 SOUTH to Myrtle Beach.</li></ol>
The driving distance is 98.7 miles per Map Quest. The driving time from Myrtle Beach to Charleston per Map Quest is 2 hours and 7 minutes.
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The driving distance from Houlton Maine to Myrtle Beach is 1236 miles per Map Quest. The driving time per Map Quest is 19 hours and 50 minutes.
The driving distance from Southport NC to Myrtle Beach SC is 64 miles per Map Quest. The driving time per Map Quest is 1 hour and 20 minutes.
The distance from Kernersville, NC to Myrtle Beach, SC is approximately 185 miles via I-40 E and US-701 S.
The driving distance between Myrtle Beach SC and Tampa FL is 553 miles per Map Quest. The driving time per Map Quest is 8 hours and 54 minutes.
The driving distance between Easton MD and Myrtle Beach SC is 514 miles per Map Quest. The driving time per Map Quest is 8 hours and 10 minutes.
The driving distance from Myrtle Beach SC is Atlanta GA is 364 miles via US-76 West to I-20 West per Map Quest. The driving time per Map Quest is 5 hours and 53 minutes.
The driving distance from Charleston SC to Myrtle Beach SC is 98 miles per Map Quest. The driving time per Map Quest is 2 hours and 2 minutes.
The driving distance is 350 miles per Map Quest. The driving time per Map Quest is 6 hours and 39 minutes.
google map, mapquest, randmcnally. all good for driving distances.
The approximate driving distance from Naples, FL to Myrtle Beach, SC is around 650-700 miles, depending on the specific route taken. It usually takes about 10-11 hours to drive this distance without factoring in traffic or stops.