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If you buy anything with "DM" in the name, it probably already had Dextromethorphan in it. So yes, Guafenesin can be taken with Dextromethorphan but taking too much Dextromethorphan can cause a few undesirable side effects.

It's unlikely that you'll be able to buy Dextromethorphan by itself anyway, it will likely come with Acetametaphin and Phenylephrine or Guafenesin.
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12y ago
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14y ago

Yes you can. There is no listed interaction between these two medications, and they have entirely different effects. Always stick to the dosages prescribed of course.

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14y ago

yes

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Q: Can you mix guaifenesin and dextromethorphan?
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No. It is a combination of an expectorant (Guaifenesin) and an cough-suppressant, (dextromethorphan). Dextromethorphan (DXM) actually possess CHOLINERGIC properties. If taken in excess, cholinergic toxidrome can be induced.


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