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It is possible, however "not preferable" is drastically understating the seriousness of it. If you put the wrong caliber cartridge in a handgun, you can possibly damage the gun and/or hurt yourself, so it isn't "not preferable." INSTEAD, it is a really, really bad idea that you should never try.

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6y ago
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6y ago

Not going to work. The .22LR cartridge is longer and skinnier than the .25 Auto. It is also a rimmed cartridge (the auto is semi rimmed) and is a rimfire cartridge- the firing pin strikes the EDGE of the cartridge. The .25 Auto is a centerfire cartridge- firing pin hit primer in the center of the cartridge face.

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Q: Can you put a .22 bullets in .25 handgun Is it possible or only not preferable?
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