Yes you can. Like if there was a pesky child, an adult, supposing either parent or teacher would say:
"You are nuisance"
OR
"(Child's Name), you are a nuisance."
The sentence is so informal that grammatical categorization runs screaming from it. Formally we say "The issue is whether it is a nuisance." Recording informal speech we write "The issue is: Is it a nuisance?"
A good sentence for nuisance would be: 'The dog was such a nuisance that we had to keep him outside all day in order to not displease our guests.'
Computer problems are a nuisance for many companies. The little boy was being a nuisance to his brother.
Like so: "That man is a nuisance!" It's the same as "That man is an annoyance!" or "annoying person."
The little boy caused so much nuisance in the class.
His constant interruptions were quite a nuisance to the class.
To be a nuisance means to be a pest, to be annoying. Example: ''The little boy was making a nuisance of himself by nagging his mom about the new toy he wanted."
I resign. I resign from student council.
My boss is a meddlesome nuisance.
The abrasion is just a minor nuisance, considering where it is located.
She earned a role in the play after a spectacualr audtion.
The mountain cabin was ablaze for only a short time.