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No. Vaccinia is "large" ... for a virus, which still means "tiny" compared to any ordinary human scale. The smallest things visible to the naked eye are on the order of 10-4 m; vaccinia is well under 10-6 m ... over a hundred times too small to see. It's just barely larger than the smallest thing visible with an optical microscope

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Q: Can you see vaccinia virus be seen with naked eye?
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