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Maybe. Seroquel can cause significant drowsiness, as can Ambien (obviously). Due to the overlapping "side effects," this combination should only be used in patients for whom a doctor has determined that the benefits outweigh the risks. In other words, your doctor will determine if this is a safe combination for you. It may not be safe for all patients.

A doctor may avoid this combination in a frail patient of advanced age due to high risk of slip-and-fall type injuries. On the other hand, the psychological benefits may exceed the risks in a different patient. If your doctor has prescribed this combination, discuss any concerns with him or her. Do not discontinue your medicine except under the advice of a doctor or pharmacist.

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Q: Can you take 400 mg of seroquel and ambien together?
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