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If you feel that the 150mg is too strong for you, yes you can. And since there is a sustained (extended) release version, that should be fine. I wouldn't break the tablet in half though. Once you break the tablet, the SR (or ER) is released. Don't stop taking Wellbutrin or any other anti-depressant cold turkey. Taper off and decrease your dosage. Wellbutrin can also be used to stop smoking. The actual brand name of it is Zyban, but their generics are the exact same.

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Q: Can you take Wellbutrin 150 mg every second day?
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