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Funny you mention this. I am on the drug and took Tylenol earlier today... not feeling too good. I am noticing my mood take a down turn. Looked it up and it is listed as one of the medications you should not take with Depakote. Good to know now, will not be mistaken again.

When you are taking any medication and need to take another one such as something for headache or cold, then phone a pharmacist and they will tell you. I do it all the time.

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12y ago
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11y ago

Yes. Two different medicines so they won't interact with each other. :)

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Q: Can you take acetaminophen if you are on depakote?
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