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Absolutely - Oxycodone and Tylenol is already marketed as a prescription drug. You know it as Percocet.

Percocet Dosages have 2 numbers, e.g., the dose I use is 10/325. The 10 indicates the amount of Oxycodone in the pill, and the 325 indicates the amount of Tylenol in the pill.

There are several doses, ranging from 2.5, 5, 7.5 and 10mg of Oxycodone, with up to 750mg of Tylenol. Depending on how much is taken, a patient may opt to go with a lower Tylenol component. For example, I use between 120/150 per month, so I use the lowest dose of Tylenol available. I can always increase the amount by taking regular Tylenol if needed.

Conversely, the combination of Oxycodone and Aspirin is known as Percodan. It's not prescribed as often because Oxycodone is already hard on the stomach if you're not used to it. Adding the Aspirin component doesn't help, so for long term pain patients like me Percocet is much easier on the system.

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15y ago
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15y ago

i would not advise it because if it was prescribed to you then it should be a bit strong so you should take that first wait a couple mins. then take the tylenol. Make sure you take it with a meal

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14y ago

The two do not have any dangerous interactions and there is actually a branded form of oxycodone and ibuprofen called Combunox. Any possible issues that may arise would be from either medicine itself, and not due to the combination.

The oxycodone should be taken as directed, and the ibuprofen doses shouldn't exceed 600mg.

As always consult your physician first.

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12y ago

Of course. Percodan is oxycodone and aspirin. A lot of pills with oxycodone in them also have Tylenol or aspirin in them.

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15y ago

Yes, there is no problem in taking those 2 drugs together.

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Q: Can you use Ibuprofen and oxycodone together?
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