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It will be pointless to use eye whitener at night whether you have been prescribed for or you bought it over the counter the purpose of it is to make your iris white, so if you use at night and wake up the next day, you'd still need to use it again. Better use a good lubricant so that your eyes don't get strained from drying when using the contacts or rather give the contacts a break if they make your eyes too blood shot that you look as if you are drunk :)

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Q: Can you use eye whitener at night and then contacts the next day?
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