yes
The R-22 (chlorodifluoromethane), will leak from a smaller hole than R-410A will. Sort of. Now that we've answered the question, it's time to state that R-410A is an azeotropic mixture of difluoromethane and pentafluoroethane. And the difluoromethane component of the mixture is a smaller molecule than chlorodifluoromethane, which is what R-22 is. But the pentafluoroethane is a larger molecule than the chlorodifluoromethane (R-22). If molecular size is the sole determinate as to which "stuff" can get out, part of the R-410A can get out a smaller hole than the R-22, but all of the R-22 can get out through the "right sized hole" because it is smaller than a constituent of the R-410A. It's your call. Links are provided.
R-22 has HCFC (hydrocloroflorocarbons) R-410A has HFC (hydroflorocarbons)
410 is better
r-22 (gentron), and r-410a (puron)
R-22 or 410A
Depends on what you are retrofiting from- to? R-22 to R-410a or r-12 to r134a?
The pressure of R-410A is significantly higher than other refrigerants R-22 and R-404A. This does not mean that R-410A, or equipment containing R-410A is unsafe. It does mean that technicians must use AC equipment; cylinders and service tools have been re-engineered to handle these higher pressures.
Any refrigeration supplier provided you have the proper federal certification.
There is two types. One is for R-22 and the other is for R-134A or R-410A. You must perform superheat and subcool, measure ambient temperature and wet bulb.
No Difference
60 psi for r-22. 125 for a 410a